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Chronic enteropathy associated with SLCO2A1 gene : ウィキペディア英語版 | Chronic enteropathy associated with SLCO2A1 gene Chronic enteropathy associated with SLCO2A1 gene is a rare autosomal recessive enteropathy that was first described in 1968.〔Okabe H, Sakimura M (1968) Nonspecific multiple ulcer of the small intestine. Stomach and Intestine 3: 1539–1549〕 This condition was previously named chronic nonspecific multiple ulcers of the small intestine.〔Matsumoto T, Iida M, Matsui T, Yao T, Watanabe H, Yao T, Okabe H (2004) Non-specific multiple ulcers of the small intestine unrelated to non-steroidal anti-inflammatory drugs. J Clin Pathol 57(11):1145-1150〕〔Matsumoto T, Iida M, Matsui T, Yao T (2007) Chronic nonspecific multiple ulcers of the small intestine: a proposal of the entity from Japanese gastroenterologists to Western enteroscopists. Gastrointest Endosc 66(3 Suppl):S99-107〕 ==Pathology==
Within the small intestine there are multiple small shallow ulcers which may be linear or concentric.〔Matsumoto T, Nakamura S, Esaki M, Yada S, Koga H, Yao T, Iida M (2006) Endoscopic features of chronic nonspecific multiple ulcers of the small intestine: comparison with nonsteroidal anti-inflammatory drug-induced enteropathy. Dig Dis Sci 51(8):1357-1363〕 Stensosis of the small bowel may be present due to healing of these ulcers. The ulcers resemble those associated with non steroidal use but occur in the absence of the use of these drugs.
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